Cocaine addiction isn’t simply a failure of willpower — it’s the result of lasting biological changes in the brain.

Scientists identify the protein DeltaFosB as the "master switch" that rewires the brain's memory and reward circuits, driving chronic cocaine addiction and relapse.

When considering the drugs most likely to cause former addicts to repeatedly relapse, opioids, cocaine, and methamphetamine ...

Researchers identify PV neurons in the prefrontal cortex as the gatekeepers of drug addiction relapse, offering a new target for precision treatment.

When a cocaine addict relapses, it isn't a matter of personal failure—it's the biological result of their brain's rewiring, ...

Health Affairs' Rob Lott interviews Nora Volkow, director of the National Institute on Drug Abuse (NIDA) at the National Institutes of Health, to discuss addiction as a brain disorder, treatments for ...

Drugs originally designed to treat diabetes and obesity are reshaping medicine in unforeseen ways. Their impact on public health is really unprecedented in modern times, perhaps only upstaged by ...

Drug addiction carries an extremely high risk of relapse, as cravings can be reignited by minor stimuli even long after one has stopped using. Previously, this phenomenon was attributed to a decline ...

Mindfulness, holistic care, and neuroscience are reshaping addiction treatment and offering hope for recovery. Mindfulness, holistic care, and neuroscience are reshaping addiction treatment and ...

Scientists don’t yet fully understand how GLP-1 drugs like Ozempic affect the brain’s reward pathways, but there are ...

“I don’t understand why he just can’t stop abusing alcohol.” Turns out that addiction is a whole lot more complicated than just saying “no.” Although the stigma of addiction as a moral failing ...