Cancer’s strongest gene switches push DNA into damaging overdrive, creating repeated breaks and repairs that may fuel tumor ...

Cancer does not develop overnight. It can take decades for cancer-promoting changes in the genome to eventually lead to the formation of a malignant tumor. Researchers at the German Cancer Research ...

Researchers at the Josep Carreras Leukaemia Research Institute propose a new view of cancer based on spatial hallmark ecosystems and its evolution during cancer progression. This conceptual framework ...

EVOFLUx uses DNA methylation fluctuations as molecular barcodes to trace tumor evolution, offering insights into growth, treatment resistance, and prognosis. The method requires only bulk methylation ...

Researchers published a new study, “Ongoing chromothripsis underpins osteosarcoma genome complexity and clonal evolution,” in Cell that they say solves the mystery of what drives the genomic ...

Editor’s note: This is an automatically generated transcript. Please notify editor@healio.com if there are concerns regarding accuracy of the transcription. Before trastuzumab-deruxtecan, we didn't ...

Survivorship evolved from enduring treatments to living a meaningful life, emphasizing daily love and giving back. Cancer altered Gillespie's life perspective, sense of invincibility, and social ...

A new study using serial liquid biopsies to track how metastatic prostate cancer evolves under treatment pressure showed that androgen receptor (AR) alterations consistently emerged and were linked to ...

Editor’s note: This is an automatically generated transcript. Please notify editor@healio.com if there are concerns regarding accuracy of the transcription. The breast cancer treatment landscape has ...