Scientists usually study the molecular machinery that controls gene expression from the perspective of a linear, two-dimensional genome—even though DNA and its bound proteins function in three ...

Sometimes, a small error in the sequence of DNA can lead to a very serious disease. Scientists have identified many mutations that arise in a single gene to cause an ...

To further the quantitative understanding of cellular decision making, Dr. Gregory Reeves and his team in the chemical engineering department have worked to interpret how a transcription factor ...

University of South Australia scientists have developed a powerful new way to uncover the genetic interactions that fuel cancer progression, paving the way for earlier and more precise treatments. The ...

The Collaborative Cross (CC) mouse resource has emerged as an indispensable platform for elucidating the genetic basis of complex traits. By combining high levels of genetic diversity from eight ...

Gene therapy that can cross the blood–brain barrier represents a non-invasive way to map gene expression in the brains of ...

A new study led by researchers at UTHealth Houston investigated both gene expression and regulation at single cell levels to reveal disruptions in gene function in three brain regions of patients with ...

An international team of researchers has shed light on why mental health conditions often occur together. Researchers analyzed data from more than 6 million people to explore the connections among ...