The DNA packed inside every human cell contains instructions for life, written in billions of letters of genetic code. Every time a cell divides, the complete code, divided among 46 chromosomes, must ...

A fleeting DNA fold called i‑DNA can switch cancer‑related genes on and off, revealing a hidden structural weak point that ...

This transcript has been edited for clarity. For more episodes, download the Medscape app or subscribe to the podcast on Apple Podcasts, Spotify, or your preferred podcast provider. Dr Liu is a ...

Researchers at the Center for Embryology and Healthy Development (CRESCO) aim to find out why so many early embryos fail in their development. New insights into how maternal and paternal DNA is ...

Sarah J. Aitken is at the Center of Molecular and Cellular Oncology, Yale Cancer Center, New Haven, Connecticut 06511, USA, and in the Department of Pathology, Yale School of Medicine, New Haven. Read ...

DNA doesn’t just sit still inside our cells — it folds, loops, and rearranges in ways that shape how genes behave. Researchers have now mapped this hidden architecture in unprecedented detail, showing ...

Movie 1: Movement of single nucleosomes in living human cells. The movie shows nucleosome fluctuations in euchromatin (left), where gene expression is active, and in heterochromatin (right), where ...

Scientists at the University of Leicester have captured the first detailed "molecular movie" showing DNA being unzipped at the atomic level – revealing how cells begin the crucial process of copying ...

G4 and R-loop signals at the indicated genomic locus. Both G4s and R-loops accumulate in cells where the resolution of G4 knots is defective (red). Not all DNA looks like the familiar twisted ladder.

For the first time, scientists have witnessed the very moment DNA begins to unravel, revealing a necessary molecular event ...