Recent advances in computational biology have revolutionised the field of protein structure and function prediction. Traditionally, determining the three‐dimensional architecture of a protein from its ...

A new LMU study shows how proteins function reliably even without a stable 3D structure—and the crucial importance not only of short sequence motifs, but also of chemical characteristics.

Astronomers use the term dark energy to refer to energy in the universe that is unaccounted for by ordinary matter but necessary to explain cosmology. Astronomy, however, isn't the only field with ...

Proteins are essential macromolecules that play a crucial role in virtually all biological processes. They are the building blocks of life, performing a wide range of functions within organisms, from ...

A new LMU study shows how proteins function reliably even without a stable 3D structure – and the crucial importance not only ...

This fully updated volume explores a wide array of new and state-of-the-art tools and resources for protein function prediction. Beginning with in-depth overviews of essential underlying computational ...

The genomes of phages—viruses that infect bacteria—are largely composed of "dark matter": genes that encode proteins whose functions remain unknown. Less than four years ago, a team led by Prof. Rotem ...

Using a tool to solve a protein's structure, for most researchers in the world of structural biology and computational ...

In the wee hours of an October morning, David Baker, a protein biologist at the University of Washington (UW), received the most-awaited phone call in a scientist’s career. Halfway around the world, ...

In a recent study published in the journal Nature Machine Intelligence, researchers developed "DeepGO-SE," a method to predict gene ontology (GO) functions from protein sequences using a large, ...

In genetics, one harmful variant can be enough to cause disease—but two can make it far more severe. One notable example is KJ, an infant diagnosed with a rare urea cycle disorder with a grim ...