Experiments in mice and observations in humans have suggested the bone protein osteocalcin acts as a hormone regulating, among other things, metabolism, fertility, exercise capacity and acute stress.

Osteocalcin is involved in the progression of nonalcoholic fatty liver disease (NAFLD) in animal models and humans. In this study we investigated the relationship between serum osteocalcin levels and ...

Bones are more than just the scaffolding for our body lumps. Bones are rigid organs filled with a honeycomb-like matrix, and while they do protect our internal organs, they also secret several ...

Researchers have found that the skeleton, acting through the bone-derived hormone osteocalcin, exerts a powerful influence on prenatal brain development and cognitive functions such as learning, ...

CI: Confidence interval; HbA1c: Glycated hemoglobin; I: Interventional study; IR: Insulin resistance; L: Longitudinal study; OR: Odds ratio; TOC: Total osteocalcin; X ...

Scientists are examining what is really behind the human fight-or-flight response—a bodily reaction to mental and physical stressors that prepares us either to stay and combat the threat (fight) or to ...

Osteocalcin (OCN) is a multifunctional bone-derived hormone that modulates numerous physiological activities. OCN can cross the blood brain barrier (BBB) and thus play critical roles in neuronal and ...

When we exercise, our bones produce a hormone called osteocalcin that increases muscle performance, according to a study publishing June 14 in a Cell Metabolism special issue on aging. Osteocalcin ...

Researchers at Columbia University Medical Center have now identified a surprising and critically important novel function of the skeleton. They've shown for the first time that the skeleton is an ...

Impaired glucose metabolism is common and contributes to the risk of diabetes and cardiovascular disease. Deletion of the gene for the osteoblast-derived protein, osteocalcin, leads to insulin ...

Experiments in mice and observations in humans have suggested the bone protein osteocalcin acts as a hormone regulating, among other things, metabolism, fertility, exercise capacity and acute stress.