Four tiny 3D organs connected themselves in a lab dish, forming a replica of the human pain pathway, in a new study. The discovery allows scientists to better understand chronic pain and how pain ...

Stanford Medicine investigators have replicated, in a lab dish, one of the most prominent human nervous pathways for sensing pain. This nerve circuit transmits sensations from the body’s skin to the ...

The American College of Cardiology (ACC) expert decision pathway for chest pain can safely and effectively rule out acute coronary syndromes in most patients, but not for those with known coronary ...

Scientists have re-created a pain pathway in the brain by growing four key clusters of human nerve cells in a dish. This laboratory model could be used to help explain certain pain syndromes, and ...

New research suggests pain is not a simple signal of injury but a process that unfolds across nerves, spinal cord, and brain. Scientists are now targeting earlier points in that pathway, before pain ...

Estrogen may cause certain colon cells, shown in green in this microscope image, to release a hormone called peptide YY. This, in turn, causes a different type of colon cell, colored magenta, to pump ...

Three floors below Dmitriy Sheyn’s lab at Cedars-Sinai Medical Center, doctors remove degenerated intervertebral discs from patients with severe back pain. Instead of tossing the old discs, however, ...

Researchers at UC Santa Barbara identified a pain pathway in fruit flies that reduces the sensation of pain from heat. The researchers discovered that just a single neuron on each side of the animal’s ...

Short-lived, acute pain is a normal response to an injury and will steadily diminish as inflammation subsides. For some, however, this kind of pain develops into a chronic condition that persists for ...