The database of 200 million protein-structure predictions now includes homodimers, adding new biological relevance.

For years, biomolecular condensates were thought to be simple, liquid-like droplets with little internal organization. New ...

Viruses are invading pathogens that infect host cells and rapidly replicate throughout the body. They carry a small piece of genetic material such as DNA or RNA surrounded by a capsid that needs a ...

Recent advances in computational biology have revolutionised the field of protein structure and function prediction. Traditionally, determining the three‐dimensional architecture of a protein from its ...

The genomes of phages—viruses that infect bacteria—are largely composed of "dark matter": genes that encode proteins whose functions remain unknown. Less than four years ago, a team led by Prof. Rotem ...

A new LMU study shows how proteins function reliably even without a stable 3D structure – and the crucial importance not only ...

Researchers from the Advanced Science Research Center at the CUNY Graduate Center (CUNY ASRC) designed an experiment to test whether performing X-ray crystallography imaging using elevated temperature ...

Researchers are using crystallography to gain a better understanding of how proteins shapeshift. The knowledge can provide valuable insight into stopping and treating diseases. Proteins do the heavy ...

AI protein function prediction uses machine learning models trained on sequence and structural data to infer protein roles at ...

A new LMU study shows how proteins function reliably even without a stable 3D structure—and the crucial importance not only of short sequence motifs, but also of chemical characteristics. Subscribe to ...

Many proteins have a complex architecture that enables biological functions. Molecules can bind to specific sites on a ...

Protein activity can be precisely regulated via subtle changes in temperature using heat-sensitive switches. Underlying this ...