The challenges of connecting molecular changes to tissue structure and highlights the potential of multifractal frameworks to quantify complex biological patterns ...

Christopher H. Contag explores how tissue regeneration involves organized interactions beyond just cell replacement, highlighting two emerging technologies ...

Combined PD-L1 expression and PD-1+ CD8 T cells to predict immunotherapy outcomes in esophageal squamous cell carcinoma. This is an ASCO Meeting Abstract from the 2025 ASCO Annual Meeting I. This ...

T cell activation—the process by which these key immune defenders recognize threats and mobilize against them—depends on exquisitely timed molecular signals. Now researchers have captured one of the ...

How does a tiny cluster of cells become an embryo with a head, trunk, and tail? And how do thousands of genes coordinate this development? A new imaging method makes it possible to visualize the ...

Spatial proteomics is a spatial biology method that helps study the spatial distribution of the proteins within cells and tissues. The subcellular localization of proteins is intrinsic to cellular ...

In organelle imaging, segmentation aims to accurately delineate pixels or voxels corresponding to target organelles from background, noise, and other cellular structures in microscopy images, thereby ...

This illustration summarizes how integrated spatial transcriptomics, single-cell transcriptomics, single-cell epigenomics, and spatial epigenomics enable multi-dimensional profiling of the tumor ...

In this GEN Learning Lab, our expert panelists Linda Orzolek, MS, MB, Xuhuai Ji, MD, PhD, and Christina Chang, PhD, will discuss the current landscape of imaging- and next-generation sequencing-based ...

Breast cancer remains one of the most prevalent and life-threatening forms of cancer, impacting millions worldwide. This malignancy's heterogeneity and complexity have long posed significant ...