The project started as undergraduate research supervised by the study’s co-corresponding author, Naoki Masuda, professor in the Department of Mathematics. That initial work carried out a somewhat ...

A biological switch that reliably turns protein expression on at will has been invented. The switch enables control of genome editing tools that might one day regulate cascades of desired genetic ...

Scientists have developed an oligonucleotide gene switch that can regulate the expression of therapeutic or cell-killing genes inserted into viruses used for gene therapy or oncolytic virotherapy.

Our genome contains thousands of genes, each of which has to be turned on and off at precisely the right times, or serious dysfunction in our bodies can result. If scientists could learn how to ...

In a recent study published in the journal Nature Biotechnology, researchers describe the pA regulator system based on a ribonucleic acid (RNA)-based switch to regulate mammalian gene expression by ...

Scientists at the MRC Laboratory of Medical Sciences (LMS) have discovered a DNA-based “dimmer switch” that regulates the activity of a critical developmental gene, Cdx2. This work could pave the way ...