Researchers used positron emission tomography, or PET, brain imaging on 32 people with AUD and 29 controls. They found 11% ...

Cognitive tasks, such as learning and memory, require rapid changes to proteins at synapses, such as protein synthesis, degradation, and trafficking. How protein post-translational modifications ...

Glutamate receptors, including AMPA and NMDA subtypes, are pivotal mediators of excitatory transmission and plasticity across the mammalian central nervous system. Their regulation, which involves ...

A study mapped genes linked to schizophrenia and uncovered a mechanism that disrupts synaptic plasticity in affected individuals. The researchers showed the role of three proteins in mediating the ...

Researchers identify the Munc13-1 protein as a crucial molecular pathway for working memory, linking calcium signaling to synaptic strengthening.

As animals experience new things, the connections between neurons, called synapses, strengthen or weaken in response to events and the activity they cause in the brain. Neuroscientists believe that ...

Neurons are important, but they are not everything. Indeed, it is "cartilage," in the form of clusters of extracellular matrix molecules called chondroitin sulfates, located in the outside nerve cells ...

By adding, removing, strengthening, or weakening synaptic contacts, our brain encodes new events or forgets previous ones. In AD, synaptic plasticity, the brain's ability to regulate the strength of ...

This mitochondrial process supports the brain cells essential to learning, memory and social recognition. We know that mitochondria are the powerhouses of the cell, but what role do they play in ...

New research on the hippocampus, a brain area essential for memory, suggests that new rules of synaptic plasticity best explain how brain activity continually reshapes the way memories are recorded in ...