A new strategy strengthens the bond between the T cell and a target tumor cell, improving the cytotoxic function of the T cell.
T cell activation—the process by which these key immune defenders recognize threats and mobilize against them—depends on ...
A cluster of recent studies has sharpened the scientific picture of how T cells switch on, tracking the molecular signals ...
Scientists have discovered that T cell receptors activate through a hidden spring-like motion that had never been seen before. This breakthrough may help explain why immunotherapy works for some ...
Chimeric antigen receptor (CAR) T-cell therapy has transformed the treatment of refractory or relapsed leukemia and hematologic malignancies, particularly over the past decade. Despite its ...
In this issue of JCO Oncology Practice, Majhail et al 1 describe their organization's experience with outpatient chimeric antigen receptor T-cell (CAR-T) cell therapy using a remote patient monitoring ...
T cell lymphomas are notoriously difficult to treat because immunotherapy, despite being one of the most effective therapies for treating cancer, can't easily distinguish cancerous T cells from ...