Researchers from UNSW Sydney have discovered that a particular transposable element, or jumping gene, in the genome has a profound effect on the immune response to virus infection. The findings in ...

Transposable elements are DNA sequences which are also known as “jumping genes”, given their ability to move from one location of the genome to another. They are present in all eukaryotic genomes and ...

New research suggests that transposable elements in various cancers potentially may be used to direct novel immunotherapies to tumors that don't typically respond to immune-based treatments. Jumping ...

The human genome contains 4.5 million copies of transposable elements (TEs), so-called selfish DNA sequences capable of moving around the genome through cut-and-paste or copy-and-paste mechanisms.

This schematic illustrates how transposable elements, derived from functional RNAs or retroviruses, shape the human genome and act as regulatory DNA elements. It highlights their essential roles in ...

The gene-silencing complex HUSH might be involved in complex disorders affecting the brain and neurons. However, its mechanism of action remains unclear. Researchers now uncover the in vivo targets ...

Long-term outcomes in GIST Trial 13-162: Phase II study of imatinib in combination with binimetinib in untreated patients with advanced gastrointestinal stromal tumor (GIST). This is an ASCO Meeting ...