Different types of lipid molecule are transported around the cell by lipid-transfer proteins. Biochemical approaches have been adapted to measure which lipids are captured by the more than 130 known ...

“We’ve never had such an in-depth map of the CD1 lipidome available,” said Patricia Barral, an immunologist at King’s College London who was not involved with the work. “It will enable us to start ...

In a recent study published in the journal Nature Metabolism, a team of researchers conducted detailed longitudinal profiling and analysis of the lipidome using plasma samples from over a hundred ...

The most common side effects of mRNA vaccines like the COVID-19 shot are well known: soreness, mild fever, and general ...

A new survey of an under-explored aspect of human biology uncovers the many roles of the body's 'greasy molecules.' The sequencing of the human genome promised a revolution in medicine, but scientists ...

Better mRNA release inside cells boosts vaccine and gene editing performance, enabled by redesigned lipid molecules that grip ...

LNPs consist of ionizable lipids, which are critical for encapsulating RNA and enabling cellular uptake. Helper lipids contribute to the structural integrity and fusion with cell membranes.

Engineers at the University of Pennsylvania have built a lipid nanoparticle that chemically fuses an IDO-pathway inhibitor with the very lipids that carry IL-12 mRNA into tumors, creating a single ...

Samia Almoughrabie does not work for, consult, own shares in or receive funding from any company or organization that would benefit from this article, and has disclosed no relevant affiliations beyond ...

BOSTON--(BUSINESS WIRE)--BPGbio, a leading biology-first, AI-powered clinical-stage biopharma company focused on mitochondrial biology and protein homeostasis, is thrilled to announce its contribution ...